Webb2 juni 2024 · Thyroid peroxidase (TPO) belongs to the family of human peroxidases together with lactoperoxidase (LPO), myeloperoxidase (MPO) and eosinophil peroxidase (EPO). Its key physiological function is biosynthesis of thyroid hormones. The human TPO gene encodes a 933-amino acid protein with a molecular weight of approximately 100 kDa. WebbBackground: Hashimoto's thyroiditis (HT) is the most common form of autoimmune thyroid disease which leads, in most cases, to hypothyroidism. HT is also classified as a multifactorial disease, which is caused by an interaction between genetic and
EMT-Related Genes Signature in Thyroid Cancer OTT
WebbThyroid peroxidase (TPO) is the key enzyme in the biosynthesis of thyroid hormones. We aimed to identify the spectrum of mutations in the TPO gene leading to hypothyroidism … WebbIn a tissue panel of 30 thyroid tumors and 12 controls, it has an expression pattern similar to thyroid peroxidase, indicating possible involvement of BC013035 in thyroid … thermometer home
A Genome Wide Search for Genes Underlying the Developmental …
Webb16 okt. 2024 · We primarily investigated the short-term associations of air pollutants with mild thyroid hormone insufficiency, ie, hypothyroxinemia and high TSH, because of emerging evidence suggesting their implications for fetal development. 12-14,19 We also examined thyroid peroxidase antibody (TPOAb) positivity on the basis of evidence … Webb13 apr. 2024 · Consequently, the thyroid gland overproduces thyroid hormones, leading to hyperthyroidism (see Glossary). By contrast, HT is a condition in which autoreactive T cells and autoantibodies destroy the thyroid, leading to hypothyroidism. The autoantibodies in HT are specific for the thyroid antigens thyroglobulin (Tg) and thyroid peroxidase (TPO). WebbTranslations in context of "Antibodies to thyroid peroxidase" in English-Italian from Reverso Context: Antibodies to thyroid peroxidase are often detected in a Graves' disease. thermometer home use