WebSep 16, 2024 · Some studies have shown that honokiol can induce cell death through paraptosis induction when treated as a single drug or combined with imatinib in leukemia cells [ 20, 21 ], indicating that paraptosis may be honokiol induced, another mode of programmed cell death. WebFeb 26, 2024 · Paraptotic cell death and necrotic cell death do not show apoptotic characteristics of pyknosis, DNA fragmentation, chromatin condensations, and caspase activations 21, but share common features ...
The Thioxotriazole Copper(II) Complex A0 Induces Endoplasmic …
WebOct 16, 2013 · One feature distinguishing paraptotic cell death from apoptotic cell death is that paraptosis is not affected by broad caspase inhibitor (data not shown). In particular, apoptosis is inhibited by caspase inhibitors whereas paraptosis is resistant to such inhibitors. Involvement of procaspase-9 in paraptosis is independent of its proteolytic ... WebPDCD5 (human programmed cell death 5) plays a significant role in apoptotic and paraptotic cell deaths. However, it was found that recombinant PDCD5 added exogenously to culture medium could also enhance programmed cell death triggered by certain stimuli. Here we show that PDCD5 has a remarkable role in intercellular transport in various cells … first nations friendship centre
The thiosemicarbazone Me2NNMe2 induces paraptosis by …
Webapoptosis. (ăp′əp-tō′sĭs, ăp′ə-tō′-) n. A natural process of self-destruction by degradative enzymes in certain cells, such as epithelial cells and erythrocytes, that are genetically … WebJan 3, 2024 · Paraptosis is a new form of programmed cell death displaying endoplasmic reticulum (ER) and/or mitochondria dilation, generally due to proteostasis disruption or redox and ion homeostasis alteration. Recent studies have highlighted that several natural compounds can trigger paraptosis in different tumor cell lines. WebMar 20, 2024 · Additional work is needed to investigate the detailed underlying mechanism by which USP10 contributes to mitochondrial dilation and subsequent paraptotic cell death in malignant breast cancer cells. first nations food security