WebJan 15, 2024 · NIH Funds NEOMED Tinnitus Researcher July 8, 2024. Otonomy Reports Positive Top-Line Results from Phase 1/2 Clinical Trial of OTO-313 in Patients with … WebFeb 6, 2024 · OTO-313: Phase 1/2 trial in tinnitus patients expected to start in the second quarter of 2024 with results in the first half of 2024. OTO-313 is an improved sustained …
Intratympanic Administration of OTO-313 Reduces Tinnitus in
The results of the OTO-313 phase 2 clinical trial were announced on August 1st, 2024 and unfortunately they were disappointing. Participants experienced no tinnitus improvement, and the research of OTO-313 as a tinnitus treatment is being discontinued. Here are the key points from the recent press … See more In July 2024, Otonomy reported positive top-line results from phase 1 of OTO-313 in patients with unilateral tinnitus (tinnitus in just one ear) of at least moderate … See more When we first posted about OTO-313, many wondered why the initial trials were only focused on unilateral tinnitus. These folks will be happy to find out that in … See more OTO-313 and similar drugs represent a brand new type of tinnitus treatment, where different drug solutions are put into the cochlea with the ultimate goal of … See more WebFeb 22, 2024 · Our focus turns to the strong pipeline we have built as recently highlighted by the successful clinical trial results for OTO-313 in tinnitus and OTO-413 in hearing loss.” Source: BioSpace He went on to say, “OTO-313 and OTO-413 each address a large patient population with significant unmet need and no approved drug therapy. lrs garage cramlington
Tinnitus Clinical Trial - Light E.N.T
WebA clinically meaningful, 13-point improvement on the TFI was observed in 43% (6/14) of OTO-313 patients at both Weeks 4 and 8 versus 13% (2/16) of placebo patients (ad hoc responder analysis, p -value < 0.05). Reductions in daily ratings of tinnitus loudness and annoyance favored OTO-313 compared with placebo. WebFeb 22, 2024 · A Phase 1/2 trial of OTO-313 in patients with unilateral tinnitus of at least moderate severity demonstrated a positive clinical response for OTO-313 using the … WebApr 22, 2024 · In the first trial, they tested up to 6 months and 43% of people treated got improvements in tinnitus and 29% (4 patients) got a greater than 20 point TFI improvement (scroll up to see charts). Interestingly, those 4 patients all had severe tinnitus. lrs frozen fish food